Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14130426 | 0.84 | THRB (0.46) | POLBNPC1RAB9AMAPTTHRB | |
| SCHEMBL20153095 | 0.82 | THRB (0.37) | POLBNPC1RAB9AMAPTTHRB | |
| SCHEMBL20148508 | 0.81 | THRB (0.41) | POLBNPC1RAB9AMAPTTHRB | |
| SCHEMBL20153118 | 0.81 | THRB (0.41) | POLBNPC1RAB9AMAPTTHRB | |
| SCHEMBL14130422 | 0.77 | THRB (0.46) | NPC1MAPTTHRBGLO1NCEH1 | |
| SCHEMBL13609834 | 0.76 | THRB (0.45) | POLBNPC1RAB9AMAPTTHRB | |
| SCHEMBL26172959 | 0.76 | KCNH2 (0.45) | NPC1RAB9ATHRBALPLALPG | |
| SCHEMBL14130412 | 0.72 | TP53 (0.51) | POLBRAB9AMAPTAHRMAPK1 | |
| SCHEMBL26172960 | 0.71 | THRB (0.44) | POLBNPC1RAB9AMAPTTHRB | |
| SCHEMBL11964796 | 0.71 | KMT2A (0.49) | NPC1RAB9AMAPTTHRBALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180134873-A1 | METHODS FOR SYNTHESIS OF END-FUNCTIONALIZED POLYOLEFINS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2018-05-17 | — | — | US | disclosed |