Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.37 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.33 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.33 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14130426 | 0.85 | THRB (0.46) | THRBMAPTNPC1RAB9APOLB | |
| SCHEMBL20153118 | 0.83 | THRB (0.41) | THRBMAPTNPC1RAB9APOLB | |
| SCHEMBL20148508 | 0.83 | THRB (0.41) | THRBMAPTNPC1RAB9APOLB | |
| SCHEMBL20148509 | 0.82 | POLB (0.36) | THRBMAPTNPC1RAB9APOLB | |
| SCHEMBL14130422 | 0.78 | THRB (0.46) | THRBMAPTNPC1GLO1KMT2A | |
| SCHEMBL13609834 | 0.77 | THRB (0.45) | THRBMAPTNPC1RAB9APOLB | |
| SCHEMBL14130412 | 0.74 | TP53 (0.51) | MAPTRAB9APOLBKMT2AMEN1 | |
| SCHEMBL26172959 | 0.73 | KCNH2 (0.45) | THRBNPC1RAB9AGLO1KMT2A | |
| SCHEMBL30277702 | 0.72 | GLO1 (0.41) | THRBMAPTNPC1RAB9APOLB | |
| SCHEMBL11964796 | 0.72 | KMT2A (0.49) | THRBMAPTNPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10414903-B2 | Methods for synthesis of end-functionalized polyolefins | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2019-09-17 | — | — | US | disclosed |
| US-20180134873-A1 | METHODS FOR SYNTHESIS OF END-FUNCTIONALIZED POLYOLEFINS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2018-05-17 | — | — | US | disclosed |