SCHEMBL20149422

SCHEMBL20149422

c1ccc2c(-c3ccc(-n4c5ccccc5c5cc(-c6ccc7c(c6)c6ccccc6n7-c6cccc7ccccc67)ccc54)cc3)cccc2c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.40
ATM Q13315 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
POLB P06746 1/20 0.40
CA12 O43570 3/20 0.39
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39
CA9 Q16790 3/20 0.39
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
ALK Q9UM73 1/20 0.36
TUBB4A P04350 1/20 0.35
TUBB P07437 1/20 0.35
TUBA3C P0DPH7 1/20 0.35
TUBA1B P68363 1/20 0.35
TUBA4A P68366 1/20 0.35
TUBB4B P68371 1/20 0.35
TUBB3 Q13509 1/20 0.35
TUBB2A Q13885 1/20 0.35
TUBB8 Q3ZCM7 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22876521 0.94 KDM4E (0.42) KDM4EATML3MBTL1POLBCA12
SCHEMBL23118789 0.94 KDM4E (0.42) KDM4EATML3MBTL1POLBCA12
SCHEMBL854367 0.93 CA12 (0.45) POLBCA12CA1CA2CA9
SCHEMBL29476054 0.93 CA12 (0.45) POLBCA12CA1CA2CA9
SCHEMBL15436115 0.93 KDM4E (0.46) KDM4EATML3MBTL1POLBCNR1
SCHEMBL23370527 0.93 KDM4E (0.46) KDM4EATML3MBTL1CA12CA1
SCHEMBL18623557 0.92 KDM4E (0.44) KDM4EATML3MBTL1POLBCNR1
SCHEMBL10130267 0.92 CA12 (0.46) KDM4EATML3MBTL1CA12CA1
SCHEMBL15479972 0.92 POLB (0.36) KDM4EATML3MBTL1POLBCA12
SCHEMBL23468811 0.92 CA12 (0.38) KDM4EATML3MBTL1POLBCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230309394-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-28 US disclosed
US-20230309394-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-28 US disclosed
US-20230139757-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-05-04 US disclosed
US-20230139757-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-05-04 US disclosed
US-20230049674-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-02-16 US disclosed
US-20230023388-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-01-26 US disclosed
US-20220173326-A1 MELT MIXTURE FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2022-06-02 US disclosed
EP-3863077-B1 ORGANIC LIGHT EMITTING DEVICE LG CHEMICAL LTD (KR) 2022-05-04 EP disclosed
EP-3863077-A1 ORGANIC LIGHT EMITTING DIODE LG Chem, Ltd. (KR) 2021-08-11 EP disclosed
EP-3832746-A1 ORGANIC LIGHT-EMITTING DEVICE LG Chem, Ltd. (KR) 2021-06-09 EP disclosed
US-20180138420-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2018-05-17 US disclosed
US-20180138420-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2018-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230049674-A1 ORGANIC LIGHT EMITTING DEVICE CRY2, ELOVL1, CRY1 KDM4E 2327/4885ATM 4301/4885L3MBTL1 213/4885
US-20180138420-A1 ORGANIC ELECTROLUMINESCENT ELEMENT EML4, LAGE3, KCNN4 KDM4E 846/4885ATM 4565/4885L3MBTL1 157/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.