Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 8/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 8/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25059485 | 0.68 | RAPGEF4 (0.43) | TAS1R3TAS1R1CRHR1 | |
| SCHEMBL20161881 | 0.67 | PRSS1 (0.39) | — | |
| SCHEMBL4860025 | 0.61 | TLR7 (0.40) | CRHR1 | |
| SCHEMBL20133814 | 0.61 | CRHR1 (0.33) | TAS1R3TAS1R1CRHR1 | |
| SCHEMBL20149895 | 0.61 | TAS1R3 (0.34) | TAS1R3TAS1R1 | |
| SCHEMBL8047103 | 0.59 | KCNH2 (0.39) | TAS1R3TAS1R1CRHR1 | |
| SCHEMBL2429720 | 0.59 | HCAR3 (0.44) | TAS1R3TAS1R1 | |
| SCHEMBL20133776 | 0.54 | ESR1 (0.34) | — | |
| SCHEMBL20133768 | 0.54 | PRKCI (0.32) | — | |
| SCHEMBL3377421 | 0.54 | CYP2D6 (0.40) | TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |