SCHEMBL20152522

SCHEMBL20152522

CC(C)c1ccc(-c2nc(-c3ccc(-c4ccccc4)cc3)nc(-c3ccc(-c4ccccc4)cc3)n2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.56
RAB9A P51151 2/20 0.48
NPC1 O15118 1/20 0.48
TP53 P04637 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
PTGS2 P35354 1/20 0.48
MAPT P10636 3/20 0.47
PAX8 Q06710 1/20 0.47
NOD2 Q9HC29 1/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
ALDH1A1 P00352 1/20 0.47
HPGD P15428 1/20 0.47
MAPK13 O15264 1/20 0.46
MAPK12 P53778 1/20 0.46
MAPK11 Q15759 1/20 0.46
MAPK14 Q16539 1/20 0.46
LMNA P02545 2/20 0.46
HTT P42858 2/20 0.45
ADORA3 P0DMS8 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23185060 1.00 L3MBTL1 (0.56) L3MBTL1RAB9ANPC1TP53NPSR1
SCHEMBL15855093 0.98 L3MBTL1 (0.58) L3MBTL1RAB9ANPC1TP53NPSR1
SCHEMBL20833031 0.89 PTGS2 (0.58) L3MBTL1RAB9APTGS2MAPTPAX8
SCHEMBL40528 0.89 PTGS2 (0.58) L3MBTL1RAB9APTGS2MAPTPAX8
SCHEMBL20152518 0.88 MEN1 (0.65) L3MBTL1RAB9ANPSR1MAPTPAX8
SCHEMBL20152520 0.88 MEN1 (0.65) L3MBTL1RAB9ANPSR1MAPTPAX8
SCHEMBL13539894 0.88 RAB9A (0.50) L3MBTL1RAB9ANPC1TP53NPSR1
Water SCHEMBL11022921 0.86 PTGS2 (0.56) L3MBTL1RAB9APTGS2MAPTPAX8
Methane SCHEMBL27572717 0.86 PTGS2 (0.56) L3MBTL1RAB9APTGS2MAPTPAX8
SCHEMBL17563608 0.85 L3MBTL1 (0.54) L3MBTL1RAB9ANPC1MAPTPAX8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11001752-B2 Double spiro organic compound and organic electronic element comprising same LG CHEM, LTD. (KR) 2021-05-11 US disclosed
US-10580996-B2 Polycyclic compound and organic light-emitting element comprising same LG CHEM, LTD. (KR) 2020-03-03 US disclosed
US-20180148640-A1 DOUBLE SPIRO ORGANIC COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-05-31 US disclosed
US-20180148640-A1 DOUBLE SPIRO ORGANIC COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-05-31 US disclosed
US-20180138421-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-05-17 US disclosed
US-20180138421-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11001752-B2 Double spiro organic compound and organic electronic element comprising same DCX, TERT, TELO2 L3MBTL1 966/4885RAB9A 3206/4885NPC1 3193/4885
US-20180138421-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME CRY2, NR2E3, CRY1 L3MBTL1 644/4885RAB9A 3322/4885NPC1 2060/4885
US-20180148640-A1 DOUBLE SPIRO ORGANIC COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME DCX, TERT, TELO2 L3MBTL1 966/4885RAB9A 3206/4885NPC1 3193/4885
US-10580996-B2 Polycyclic compound and organic light-emitting element comprising same CRY2, NR2E3, CRY1 L3MBTL1 644/4885RAB9A 3322/4885NPC1 2060/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.