SCHEMBL20154155

SCHEMBL20154155

CNc1cc(CS)cc(CS)c1

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CXCR4 P61073 1/20 0.35
IDO1 P14902 4/20 0.35
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21233397 0.77 IDO1 (0.48) IDO1TSHR
SCHEMBL63291 0.76 IDO1 (0.47) IDO1
SCHEMBL25680596 0.76 SIGMAR1 (0.36) CXCR4TSHR
Hydrochloric Acid SCHEMBL8194559 0.75 IDO1 (0.46) IDO1TSHR
SCHEMBL12126049 0.74 ACHE (0.42) CXCR4TSHR
SCHEMBL26431768 0.74 KDM4E (0.42) CXCR4TSHR
SCHEMBL14899868 0.74 IDO1 (0.52) IDO1TSHR
SCHEMBL17050035 0.74 AOC1 (0.37) CXCR4TSHR
SCHEMBL19844318 0.70 PTGS2 (0.36) CXCR4TSHR
SCHEMBL21779615 0.70 GABRA1 (0.36) CXCR4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018089648-A2 DI-SULFIDE CONTAINING CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2018-05-17 WO disclosed