Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19844318 | 0.94 | PTGS2 (0.36) | SIGMAR1CXCR4PTGS2MAPTMEN1 | |
| SCHEMBL25112401 | 0.89 | ACHE (0.36) | SIGMAR1CXCR4PTGS2MAPTMEN1 | |
| SCHEMBL11259766 | 0.85 | RAPGEF4 (0.42) | PTGS2MAPTMEN1APAF1USP2 | |
| SCHEMBL3234059 | 0.84 | ALDH1A1 (0.41) | SIGMAR1PTGS2MAPTMEN1APAF1 | |
| SCHEMBL19629185 | 0.80 | NPC1 (0.30) | SIGMAR1ALDH1A1NPC1RAB9ACYP1A2 | |
| SCHEMBL3190908 | 0.80 | RAPGEF4 (0.39) | SIGMAR1PTGS2MAPTMEN1APAF1 | |
| SCHEMBL439074 | 0.78 | PTGS2 (0.48) | PTGS2MAPTMEN1APAF1USP2 | |
| SCHEMBL28806252 | 0.78 | PTGS2 (0.48) | PTGS2MAPTMEN1APAF1USP2 | |
| SCHEMBL22549038 | 0.77 | CREBBP (0.32) | MAPTMEN1APAF1USP2ALDH1A1 | |
| SCHEMBL17615244 | 0.76 | BACE1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203055-A1 | FUSED RING COMPOUND AND APPLICATION THEREOF IN MEDICINE | BETTA PHARMACEUTICALS CO., LTD (CN) | 2023-06-29 | — | — | US | disclosed |
| US-20110256130-A1 | METHODS OF TREATING INFLAMMATORY DISORDERS | SQUARE 1 BANK | 2011-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203055-A1 | FUSED RING COMPOUND AND APPLICATION THEREOF IN MEDICINE | VIP, CYP11B2, CYP11B1 | SIGMAR1 3444/4885CXCR4 52/4885PTGS2 496/4885 |
| US-20110256130-A1 | METHODS OF TREATING INFLAMMATORY DISORDERS | TNF, MPO, MMP8 | SIGMAR1 2100/4885CXCR4 508/4885PTGS2 43/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.