Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.38 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.38 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.38 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10150960 | 0.90 | PDE10A (0.42) | SMN1; SMN2NPC1THRBLMNAMEN1 | |
| SCHEMBL2013388 | 0.89 | THRB (0.39) | LIPGNPC1RAB9AALDH1A1THRB | |
| SCHEMBL2010877 | 0.88 | L3MBTL1 (0.48) | SMN1; SMN2NPC1RAB9AALDH1A1TDP1 | |
| SCHEMBL10150652 | 0.79 | THRB (0.50) | SMN1; SMN2RAB9AALDH1A1THRBTDP1 | |
| SCHEMBL10150590 | 0.78 | PDE10A (0.42) | THRBLMNAKMT2AALOX15MAPK1 | |
| SCHEMBL1973915 | 0.75 | PPARG (0.37) | RAB9A | |
| SCHEMBL1979905 | 0.73 | P2RX7 (0.43) | — | |
| SCHEMBL1975060 | 0.71 | PPARG (0.40) | SMN1; SMN2ALDH1A1LMNAMEN1TP53 | |
| SCHEMBL1974078 | 0.68 | ALDH1A1 (0.45) | ALDH1A1THRBTDP1LMNAMEN1 | |
| SCHEMBL10150961 | 0.67 | PPARG (0.40) | LMNAHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011072691-A1 | PYRIDONE DERIVATIVES AS NK3 ANTAGONISTS | H. LUNDBECK A/S (DK) | 2011-06-23 | — | — | WO | claimed |