Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 3/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13470480 | 0.81 | CYP11B2 (0.42) | SLC6A4CYP11B1CYP11B2HRH3HRH2 | |
| SCHEMBL17670005 | 0.80 | KIF11 (0.40) | QDPRSLC6A4CYP11B1CYP11B2HRH3 | |
| SCHEMBL10287528 | 0.78 | QDPR (0.54) | QDPRSLC6A4 | |
| SCHEMBL16565762 | 0.78 | QDPR (0.53) | QDPR | |
| SCHEMBL12488982 | 0.72 | GPR119 (0.51) | CYP11B2 | |
| SCHEMBL250013 | 0.72 | CYP11B2 (0.42) | CYP11B1CYP11B2HRH3KCNH2 | |
| SCHEMBL23219124 | 0.70 | SLC6A4 (0.46) | QDPRSLC6A4 | |
| SCHEMBL29591400 | 0.70 | SLC6A4 (0.46) | QDPRSLC6A4 | |
| SCHEMBL21038276 | 0.70 | CHRNB2 (0.49) | QDPRSLC6A4CYP11B1CYP11B2 | |
| SCHEMBL6135618 | 0.70 | HRH3 (0.50) | HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089904-A1 | HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS | 3-V BIOSCIENCES, INC. (US) | 2018-05-17 | — | — | WO | disclosed |