Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | PHGDH | O43175 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20157214 | 0.88 | SLC6A7 (0.36) | KDM4EALDH1A1USP2POLBKMT2A | |
| SCHEMBL20157292 | 0.86 | MCHR1 (0.31) | — | |
| SCHEMBL20156915 | 0.83 | LMNA (0.33) | LMNAKDM4EALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL20157531 | 0.74 | FAAH (0.39) | FAAHHTTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL20157038 | 0.74 | SLC6A7 (0.38) | KDM4EALDH1A1POLBKMT2A | |
| SCHEMBL20157229 | 0.72 | — | — | |
| SCHEMBL20157271 | 0.71 | MC4R (0.38) | FAAHHTTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL20157537 | 0.70 | ALDH1A1 (0.33) | HTTLMNAKDM4EALDH1A1NPSR1 | |
| SCHEMBL20156907 | 0.70 | HTT (0.38) | FAAHHTTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL20157301 | 0.69 | HTT (0.35) | FAAHHTTLMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |