Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CHKA | P35790 | 2/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20156912 | 0.70 | FAAH (0.38) | ALDH1A1LMNAKMT2APOLBKDM4E | |
| SCHEMBL20157171 | 0.70 | GRM1 (0.43) | ALDH1A1MEN1KMT2AKDM4ENPSR1 | |
| SCHEMBL20157214 | 0.62 | SLC6A7 (0.36) | ALDH1A1MEN1HPGDKMT2AHSD17B10 | |
| SCHEMBL20139955 | 0.61 | KDM4E (0.52) | ALDH1A1LMNAKDM4ENPSR1HTR7 | |
| SCHEMBL20141481 | 0.61 | KDM4E (0.51) | ALDH1A1LMNAKDM4ENPSR1HTR7 | |
| SCHEMBL20140044 | 0.60 | MTOR (0.54) | ALDH1A1MEN1KMT2AKDM4ENPSR1 | |
| SCHEMBL20157023 | 0.59 | TP53 (0.35) | ALDH1A1LMNAHPGDKDM4EHTT | |
| SCHEMBL20156931 | 0.59 | MTOR (0.51) | ALDH1A1KDM4ENPSR1PARP1HTR7 | |
| SCHEMBL20140770 | 0.58 | ALDH1A1 (0.51) | ALDH1A1LMNAKDM4ENPSR1HTT | |
| SCHEMBL20157531 | 0.57 | FAAH (0.39) | ALDH1A1LMNAKMT2APOLBHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |