Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.44 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.36 |
| ▸ | KHK | P50053 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3628472 | 0.77 | TRPV4 (0.50) | TRPV4KHKUSP30BACE2ADRB2 | |
| SCHEMBL20156944 | 0.77 | TRPV4 (0.40) | TRPV4KHKUSP30BACE2ADRB2 | |
| SCHEMBL21180029 | 0.74 | KAT2B (0.49) | FERMT2USP30ALDH1A1KDM4EKAT2B | |
| SCHEMBL3186092 | 0.73 | TRPV4 (0.50) | TRPV4KHKUSP30BACE2ADRB2 | |
| SCHEMBL6651303 | 0.73 | TRPV4 (0.71) | TRPV4KHKALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL24056640 | 0.72 | CHEK1 (0.49) | FERMT2CHEK1 | |
| SCHEMBL21704265 | 0.71 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL26106182 | 0.71 | ACLY (0.36) | TRPV4BACE2ADRB2ADRB1 | |
| SCHEMBL30317451 | 0.70 | TSHR (0.58) | FERMT2ALDH1A1KDM4ECA12CA3 | |
| SCHEMBL20156858 | 0.70 | TSHR (0.58) | FERMT2ALDH1A1KDM4ECA12CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |