Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 6/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | LOX | P28300 | 1/20 | 0.33 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20160016 | 0.77 | — | — | |
| SCHEMBL20159656 | 0.68 | CHRNA3 (0.39) | CYP17A1CHRM4LOXLOXL3LOXL2 | |
| SCHEMBL18952559 | 0.67 | CHRM4 (0.38) | CYP17A1CHRM4LOXLOXL3LOXL2 | |
| SCHEMBL20609193 | 0.67 | CHRM4 (0.38) | CYP17A1CHRM4LOXLOXL3LOXL2 | |
| SCHEMBL20609194 | 0.67 | CHRM4 (0.38) | CYP17A1CHRM4LOXLOXL3LOXL2 | |
| SCHEMBL18970901 | 0.67 | CHRM4 (0.38) | CYP17A1CHRM4LOXLOXL3LOXL2 | |
| SCHEMBL20031740 | 0.67 | CHRM4 (0.38) | CYP17A1CHRM4LOXLOXL3LOXL2 | |
| SCHEMBL2272239 | 0.66 | HTR3E (0.47) | CYP17A1 | |
| SCHEMBL20159670 | 0.66 | LOX (0.32) | CYP17A1CHRM4LOXLOXL3LOXL2 | |
| SCHEMBL20159647 | 0.66 | CHRNB2 (0.40) | CYP17A1LOXLOXL3LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538516-B1 | PHENOXYTRIAZOLES | HOFFMANN LA ROCHE (CH) | 2021-06-16 | — | — | EP | disclosed |
| WO-2018087018-A1 | PHENOXYTRIAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2018-05-17 | — | — | WO | disclosed |