Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20162233 | 0.89 | LMNA (0.54) | ACACB | |
| SCHEMBL20395698 | 0.85 | PPARG (0.62) | ACACBLDHA | |
| SCHEMBL20162264 | 0.85 | LDHA (0.67) | ACACBLDHA | |
| SCHEMBL11242410 | 0.83 | LDHA (0.68) | ACACBLDHA | |
| SCHEMBL16669459 | 0.80 | LDHA (0.42) | LDHA | |
| SCHEMBL20162271 | 0.80 | FOS (0.46) | LDHA | |
| SCHEMBL16732096 | 0.80 | TSHR (0.58) | LDHA | |
| SCHEMBL27928968 | 0.79 | ACACB (0.52) | ACACB | |
| SCHEMBL7752956 | 0.78 | ACACB (0.55) | ACACB | |
| SCHEMBL8338687 | 0.78 | GAA (0.46) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180207080-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2018-07-26 | — | — | US | disclosed |
| EP-3322400-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | Merck Patent GmbH (DE) | 2018-05-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180207080-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | LPO, CAT, GPX4 | ACACB 1406/4885LDHA 3865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.