Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | ACACB | O00763 | 5/20 | 0.52 |
| ▸ | PPARG | P37231 | 4/20 | 0.50 |
| ▸ | PPARD | Q03181 | 3/20 | 0.50 |
| ▸ | PPARA | Q07869 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20162239 | 0.89 | ACACB (0.51) | ACACB | |
| SCHEMBL20395690 | 0.85 | PPARG (0.67) | LMNAL3MBTL1ACACBPPARGPPARD | |
| SCHEMBL20162264 | 0.81 | LDHA (0.67) | L3MBTL1ACACBPPARGPPARDPPARA | |
| SCHEMBL20162275 | 0.80 | FOS (0.43) | — | |
| SCHEMBL28512690 | 0.79 | PPARG (0.67) | ACACBPPARGPPARDPPARA | |
| SCHEMBL20395656 | 0.77 | SMN1; SMN2 (0.41) | PPARGPPARDPPARAALDH1A1 | |
| SCHEMBL16669459 | 0.76 | LDHA (0.42) | LMNAPPARGPPARDPPARA | |
| SCHEMBL16732096 | 0.76 | TSHR (0.58) | CYP2C19ALDH1A1 | |
| SCHEMBL28886878 | 0.76 | LMNA (0.56) | LMNAL3MBTL1ACACB | |
| SCHEMBL13889410 | 0.76 | LMNA (0.54) | LMNAL3MBTL1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180207080-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2018-07-26 | — | — | US | disclosed |
| EP-3322400-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | Merck Patent GmbH (DE) | 2018-05-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180207080-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | LPO, CAT, GPX4 | LMNA 2333/4885L3MBTL1 4767/4885ACACB 1406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.