Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.44 |
| ▸ | PPARD | Q03181 | 5/20 | 0.44 |
| ▸ | PPARA | Q07869 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PTPRB | P23467 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20162248 | 0.88 | PPARG (0.43) | PPARGPPARDPPARAALDH1A1CYP3A4 | |
| SCHEMBL20395656 | 0.86 | SMN1; SMN2 (0.41) | PPARGPPARDPPARAALDH1A1CYP3A4 | |
| SCHEMBL20162253 | 0.85 | PPARG (0.47) | PPARGPPARDPPARACYP3A4SMN1; SMN2 | |
| SCHEMBL20395550 | 0.83 | LDHA (0.50) | PPARGPPARDPPARAALDH1A1CYP3A4 | |
| SCHEMBL20395674 | 0.79 | ALDH1A1 (0.44) | PPARGALDH1A1CYP3A4CYP2C9SMN1; SMN2 | |
| SCHEMBL20395690 | 0.76 | PPARG (0.67) | PPARGPPARDPPARAPTPRBLDHA | |
| SCHEMBL491022 | 0.74 | LDHA (0.47) | ALDH1A1ALOX5LDHAKDM4E | |
| SCHEMBL20162240 | 0.73 | CYP2D6 (0.39) | ALDH1A1CYP3A4SMN1; SMN2LDHAHSD17B10 | |
| SCHEMBL29200149 | 0.73 | PTGS2 (0.42) | ALDH1A1ALOX5MAPTHSD17B10KDM4E | |
| SCHEMBL20162238 | 0.73 | LDHA (0.50) | CYP3A4SMN1; SMN2LDHAHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180207080-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2018-07-26 | — | — | US | disclosed |
| EP-3322400-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | Merck Patent GmbH (DE) | 2018-05-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180207080-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | LPO, CAT, GPX4 | PPARG 198/4885PPARD 339/4885PPARA 249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.