Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20162240 | 0.89 | CYP2D6 (0.39) | SMN1; SMN2ALDH1A1ALOX15KDM4EGAA | |
| SCHEMBL20162255 | 0.86 | PPARG (0.44) | SMN1; SMN2ALOX5ALDH1A1PPARGKDM4E | |
| SCHEMBL20162275 | 0.85 | FOS (0.43) | SMN1; SMN2ALOX15KDM4ELDHACYP3A4 | |
| SCHEMBL20162267 | 0.82 | LDHA (0.46) | ALOX5ALDH1A1KDM4EGAALDHA | |
| SCHEMBL20162233 | 0.77 | LMNA (0.54) | ALDH1A1PPARGPPARDPPARA | |
| SCHEMBL20395674 | 0.76 | ALDH1A1 (0.44) | SMN1; SMN2ALOX5ALDH1A1PPARGHSD17B10 | |
| SCHEMBL20162271 | 0.74 | FOS (0.46) | ALDH1A1ALOX15KDM4EGAAHSD17B10 | |
| SCHEMBL20162248 | 0.74 | PPARG (0.43) | ALDH1A1PPARGKDM4ELDHAMAPT | |
| SCHEMBL29200149 | 0.71 | PTGS2 (0.42) | ALOX5ALDH1A1KDM4EGAAHSD17B10 | |
| SCHEMBL20162253 | 0.71 | PPARG (0.47) | SMN1; SMN2ALOX5ALOX15PPARGKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180207080-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2018-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180207080-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | LPO, CAT, GPX4 | SMN1; SMN2 1302/4885ALOX5 573/4885ALDH1A1 1313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.