Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HSPB1 | P04792 | 4/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27361987 | 0.84 | ERN1 (0.47) | ALDH1A1TGM2KMT2AMEN1MAPT | |
| SCHEMBL28713221 | 0.83 | ALDH1A1 (0.44) | ALDH1A1HIF1AHSPB1KMT2AMEN1 | |
| SCHEMBL28376956 | 0.82 | ALDH1A1 (0.49) | ALDH1A1TGM2KMT2AMAPTLMNA | |
| SCHEMBL7126316 | 0.81 | GPR35 (0.47) | ALDH1A1TGM2KMT2AMEN1GAA | |
| SCHEMBL4655499 | 0.81 | TTR (0.49) | ALDH1A1HIF1AHSPB1KMT2AMEN1 | |
| SCHEMBL5505279 | 0.80 | CYP4F2 (0.54) | ALDH1A1HIF1AHSPB1KMT2AMEN1 | |
| SCHEMBL15546554 | 0.80 | ALDH1A1 (0.50) | ALDH1A1HIF1AHSPB1KMT2AMEN1 | |
| SCHEMBL10180753 | 0.78 | CES2 (0.41) | TGM2KMT2AMEN1MAPTHTT | |
| SCHEMBL20424921 | 0.77 | ALDH1A1 (0.51) | ALDH1A1HIF1AHSPB1KMT2AMAPT | |
| SCHEMBL27590300 | 0.77 | ALDH1A1 (0.46) | ALDH1A1HIF1AHSPB1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3322296-A1 | SUBSTITUTED OXO-TETRAHYDROQUINOLINYL-PHOSPHINIC ACID AND PHOSPHINIC ACID AMIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS | Bayer CropScience Aktiengesellschaft (DE) | 2018-05-23 | — | — | EP | disclosed |