Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4268833 | 0.89 | POLB (0.33) | MMP9MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL10004996 | 0.88 | TAS1R3 (0.39) | ALOX15TAS1R3TAS1R1MEN1KMT2A | |
| SCHEMBL10003812 | 0.86 | CTSS (0.39) | MMP1ALDH1A1LMNASMN1; SMN2NPC1 | |
| SCHEMBL10004648 | 0.86 | ALOX15 (0.39) | ALOX15ADAM17MMP1MMP3MMP9 | |
| SCHEMBL4633796 | 0.83 | HPGD (0.36) | LMNASMN1; SMN2MAPTMAPK1HTT | |
| SCHEMBL7795340 | 0.72 | SMN1; SMN2 (0.38) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL645087 | 0.72 | RAB9A (0.41) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL10004534 | 0.72 | NPC1 (0.36) | MMP3MMP9ALDH1A1NPC1RAB9A | |
| SCHEMBL12496550 | 0.70 | MAPT (0.38) | KDM4EALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL9814756 | 0.69 | ANPEP (0.33) | ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928475-B1 | ANTIVIRAL PHOSPHORAMIDATES OF 4'-C-AZIDO-SUBSTITUTED PRONUCLEOTIDES | RIBOSCIENCE LLC (US) | 2018-05-23 | — | — | EP | disclosed |