SCHEMBL20164586

SCHEMBL20164586

CCCNc1nc(NC)nc2c(NCC(O)C(F)(F)F)nc(NC)nc12

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 4/20 0.41
CDK2 P24941 1/20 0.35
CDK9 P50750 1/20 0.35
TLR7 Q9NYK1 1/20 0.35
PKM P14618 1/20 0.33
IRAK1 P51617 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL20164547 0.99 SLC29A1 (0.40) SLC29A1CDK2CDK9TLR7PKM
SCHEMBL20164390 0.88 SLC29A1 (0.40) SLC29A1CDK2CDK9PKM
Hydrochloric Acid SCHEMBL20164571 0.86 SLC29A1 (0.40) SLC29A1CDK2CDK9PKM
SCHEMBL20164371 0.86 SLC29A1 (0.43) SLC29A1TLR7
Hydrochloric Acid SCHEMBL20164604 0.84 SLC29A1 (0.42) SLC29A1TLR7
SCHEMBL20164624 0.84 SLC29A1 (0.44) SLC29A1CDK2CDK9TLR7
SCHEMBL20164310 0.84 SLC29A1 (0.44) SLC29A1CDK2CDK9TLR7
SCHEMBL20164496 0.84 SLC29A1 (0.44) SLC29A1CDK2CDK9TLR7
SCHEMBL20164539 0.83 SLC29A1 (0.38) SLC29A1CDK2CDK9TLR7PKM
Hydrochloric Acid SCHEMBL20164587 0.83 SLC29A1 (0.43) SLC29A1CDK2CDK9TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180141953-A1 Novel Breathing Control Modulating Compounds, and Methods of Making and Using Same NEURAD LTD. (IL) 2018-05-24 US claimed
US-20250057848-A1 GAL475 COMPOSITIONS AND METHODS OF USE THEREOF NEURIM PHARMACEUTICALS (1991) LTD. (IL) 2025-02-20 US disclosed
EP-3316890-B1 NOVEL BREATHING CONTROL MODULATING COMPOUNDS, AND METHODS OF MAKING AND USING SAME NEURAD LTD (IL) 2023-09-06 EP disclosed
EP-3316890-B1 NOVEL BREATHING CONTROL MODULATING COMPOUNDS, AND METHODS OF MAKING AND USING SAME NEURAD LTD (IL) 2023-09-06 EP disclosed
US-10294228-B2 Breathing control modulating compounds, and methods of making and using same NEURAD LTD. (IL) 2019-05-21 US disclosed
US-10294228-B2 Breathing control modulating compounds, and methods of making and using same NEURAD LTD. (IL) 2019-05-21 US disclosed
US-20180141953-A1 Novel Breathing Control Modulating Compounds, and Methods of Making and Using Same NEURAD LTD. (IL) 2018-05-24 US disclosed
US-20180141953-A1 Novel Breathing Control Modulating Compounds, and Methods of Making and Using Same NEURAD LTD. (IL) 2018-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180141953-A1 Novel Breathing Control Modulating Compounds, and Methods of Making and Using Same MTNR1B, CHRM3, PER2 SLC29A1 4472/4885CDK2 4026/4885CDK9 4092/4885
US-20250057848-A1 GAL475 COMPOSITIONS AND METHODS OF USE THEREOF GPR119, GPR35, GPR55 SLC29A1 2077/4885CDK2 3942/4885CDK9 3728/4885
US-10294228-B2 Breathing control modulating compounds, and methods of making and using same MTNR1B, PDE3A, CHRM3 SLC29A1 4518/4885CDK2 4190/4885CDK9 4292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.