SCHEMBL20165457

SCHEMBL20165457

CCCCN(C(=O)OC)C(C)CC(=O)OCC

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.37
MGAM O43451 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
ALDH1A1 P00352 4/20 0.34
CYP3A4 P08684 2/20 0.34
ALOX15 P16050 2/20 0.34
TSHR P16473 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CHRM1 P11229 1/20 0.33
ADORA1 P30542 1/20 0.33
HSD17B10 Q99714 1/20 0.33
KDM5A P29375 2/20 0.32
ZDHHC7 Q9NXF8 1/20 0.32
CYP1A2 P05177 1/20 0.32
TRPA1 O75762 1/20 0.32
KMT2A Q03164 3/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20168886 0.91 ALDH1A1 (0.37) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL20165345 0.87 ALDH1A1 (0.37) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL20166109 0.87 LMNA (0.39) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL11838189 0.86 GAA (0.38) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL21522838 0.85 MAPT (0.33) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL20165352 0.84 CTSK (0.34) GAAMGAMSIMGAM2CA1
SCHEMBL21522901 0.84 DNM1 (0.36) ALDH1A1HSD17B10POLBMAPT
SCHEMBL28488965 0.83 GPR84 (0.36) CA1CA2KDM5ACYP1A2
SCHEMBL20180241 0.81 MGAM (0.38) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL21522945 0.79 ALDH1A1 (0.40) ALDH1A1TSHRTDP1HSD17B10KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3541857-B1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2020-09-09 EP disclosed
US-10654946-B2 Catalyst components for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2020-05-19 US disclosed
US-20190330388-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2019-10-31 US disclosed
EP-3541857-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2019-09-25 EP disclosed
WO-2018091375-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2018-05-24 WO disclosed