Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8565231 | 0.76 | MEN1 (0.52) | USP2HSD17B10MEN1KMT2ABRD4 | |
| SCHEMBL8565227 | 0.76 | MEN1 (0.52) | USP2HSD17B10MEN1KMT2ABRD4 | |
| SCHEMBL23580062 | 0.75 | TSHR (0.44) | MEN1KMT2ABRD4TSHRALDH1A1 | |
| SCHEMBL21723493 | 0.74 | DRD2 (0.54) | USP2HSD17B10MEN1KMT2AKDM4E | |
| SCHEMBL7209206 | 0.73 | ACHE (0.60) | USP2HSD17B10MEN1KMT2A | |
| SCHEMBL7264952 | 0.72 | MEN1 (0.48) | USP2HSD17B10MEN1KMT2ABRD4 | |
| SCHEMBL6333612 | 0.72 | OPRK1 (0.53) | USP2HSD17B10OPRK1TACR1 | |
| SCHEMBL10559750 | 0.72 | MEN1 (0.54) | USP2HSD17B10MEN1KMT2AKDM4E | |
| Fluorobenzene SCHEMBL27378912 | 0.71 | TACR1 (0.48) | USP2HSD17B10MEN1KMT2ATACR1 | |
| SCHEMBL7484195 | 0.71 | ACHE (0.68) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9977024-B2 | Targeted covalent probes and inhibitors of proteins containing redox-sensitive cysteines | THE SCRIPPS RESEARCH INSTITUTE (US) | 2018-05-22 | — | — | US | disclosed |