Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | COMT | P21964 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7264960 | 0.77 | ALDH1A1 (0.53) | HSD17B10COMTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7209206 | 0.74 | ACHE (0.60) | MEN1KMT2AUSP2HSD17B10 | |
| SCHEMBL10559750 | 0.73 | MEN1 (0.54) | MEN1KMT2AUSP2HSD17B10COMT | |
| SCHEMBL21723493 | 0.72 | DRD2 (0.54) | MEN1KMT2AUSP2HSD17B10KDM4E | |
| SCHEMBL20169545 | 0.72 | USP2 (0.53) | MEN1KMT2AUSP2HSD17B10BRD4 | |
| SCHEMBL4002090 | 0.72 | MEN1 (0.66) | MEN1KMT2AUSP2HSD17B10KDM4E | |
| SCHEMBL7484195 | 0.72 | ACHE (0.68) | MEN1KMT2A | |
| SCHEMBL29585298 | 0.71 | PTGS1 (0.61) | MEN1KMT2AUSP2HSD17B10KDM4E | |
| SCHEMBL7218634 | 0.71 | PTGS1 (0.61) | MEN1KMT2AUSP2HSD17B10KDM4E | |
| SCHEMBL5536939 | 0.71 | MEN1 (0.48) | MEN1KMT2AUSP2HSD17B10ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003099801-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2003-12-04 | — | — | WO | claimed |