Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 4/20 | 0.33 |
| ▸ | PGR | P06401 | 3/20 | 0.33 |
| ▸ | AR | P10275 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20170874 | 0.89 | ALOX5 (0.33) | NR3C1PGRARGAA | |
| SCHEMBL20170821 | 0.84 | GAA (0.36) | GAA | |
| SCHEMBL20170832 | 0.83 | NR3C1 (0.31) | NR3C1PGRAR | |
| SCHEMBL10222583 | 0.77 | OPRM1 (0.33) | GAA | |
| SCHEMBL20170595 | 0.76 | GAA (0.36) | GAA | |
| SCHEMBL20170666 | 0.76 | GAA (0.37) | NR3C1PGRARGAA | |
| SCHEMBL20170664 | 0.75 | GAA (0.36) | GAA | |
| SCHEMBL20170851 | 0.74 | GAA (0.34) | GAA | |
| SCHEMBL12646334 | 0.70 | OPRM1 (0.48) | GAA | |
| SCHEMBL20170598 | 0.69 | OPRM1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2453895-B1 | (+) - MORPHINANS AS ANTAGONISTS OF TOLL-LIKE RECEPTOR 9 AND THERAPEUTIC USES THEREOF | MALLINCKRODT LLC (US) | 2018-05-23 | — | — | EP | disclosed |