Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20170874 | 0.88 | ALOX5 (0.33) | GAAMEN1KMT2A | |
| SCHEMBL20170666 | 0.87 | GAA (0.37) | GAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20170821 | 0.86 | GAA (0.36) | GAA | |
| SCHEMBL20170756 | 0.84 | TRPV1 (0.34) | GAATRPV1 | |
| SCHEMBL20170707 | 0.76 | GAA (0.35) | GAAMEN1KMT2AUSP2LMNA | |
| SCHEMBL20170718 | 0.75 | GAA (0.36) | GAASMN1; SMN2 | |
| SCHEMBL20170609 | 0.75 | NR3C1 (0.33) | GAA | |
| SCHEMBL20170851 | 0.72 | GAA (0.34) | GAA | |
| SCHEMBL20170840 | 0.72 | GAA (0.41) | GAATSHRSMN1; SMN2 | |
| SCHEMBL12945025 | 0.70 | GAA (0.38) | GAAMEN1KMT2AUSP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2453895-B1 | (+) - MORPHINANS AS ANTAGONISTS OF TOLL-LIKE RECEPTOR 9 AND THERAPEUTIC USES THEREOF | MALLINCKRODT LLC (US) | 2018-05-23 | — | — | EP | disclosed |