Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.43 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2012666 | 0.79 | TAAR1 (0.47) | TAAR1NT5EMAOB | |
| SCHEMBL2015154 | 0.78 | TAAR1 (0.41) | TAAR1NT5ECCNT1CDK9DPP4 | |
| SCHEMBL2015779 | 0.75 | PIK3CD (0.44) | TAAR1L3MBTL1 | |
| SCHEMBL12491178 | 0.74 | BCL2 (0.47) | TAAR1NT5EDPP4 | |
| SCHEMBL9952729 | 0.68 | PIK3CD (0.44) | TAAR1 | |
| Trifluoroacetic Acid SCHEMBL2012078 | 0.68 | BCL2 (0.41) | TAAR1NT5E | |
| SCHEMBL9953114 | 0.68 | TAAR1 (0.38) | TAAR1 | |
| SCHEMBL9953794 | 0.67 | TAAR1 (0.40) | TAAR1 | |
| SCHEMBL9953176 | 0.67 | LMNA (0.39) | TAAR1L3MBTL1 | |
| SCHEMBL9953509 | 0.67 | ADORA1 (0.40) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011075630-A1 | SUBSTITUTED FUSED ARYL AND HETEROARYL DERIVATIVES AS PI3K INHIBITORS | INCYTE CORPORATION (US) | 2011-06-23 | — | — | WO | disclosed |