Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 10/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20170617 | 1.00 | HTR1A (0.32) | HTR1ANQO2MTNR1AMTNR1B | |
| SCHEMBL20170624 | 0.88 | MTNR1A (0.35) | HTR1ANQO2MTNR1AMTNR1B | |
| SCHEMBL20170600 | 0.80 | OPRM1 (0.39) | NQO2MTNR1AMTNR1B | |
| SCHEMBL20170697 | 0.80 | HTR1A (0.34) | HTR1A | |
| SCHEMBL20170645 | 0.80 | OPRM1 (0.39) | NQO2MTNR1AMTNR1B | |
| SCHEMBL20170640 | 0.80 | HTR1A (0.34) | HTR1A | |
| SCHEMBL18473575 | 0.73 | HCRTR1 (0.36) | — | |
| SCHEMBL20170641 | 0.73 | ADRA1A (0.34) | HTR1ANQO2MTNR1AMTNR1B | |
| SCHEMBL20170728 | 0.71 | OPRM1 (0.37) | NQO2MTNR1AMTNR1B | |
| SCHEMBL20170605 | 0.71 | ADRA1A (0.35) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2453895-B1 | (+) - MORPHINANS AS ANTAGONISTS OF TOLL-LIKE RECEPTOR 9 AND THERAPEUTIC USES THEREOF | MALLINCKRODT LLC (US) | 2018-05-23 | — | — | EP | disclosed |