Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ACSS2 | Q9NR19 | 9/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | SCNN1A | P37088 | 1/20 | 0.35 |
| ▸ | SCNN1B | P51168 | 1/20 | 0.35 |
| ▸ | SCNN1G | P51170 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2017836 | 0.88 | HTT (0.46) | HTTACSS2MEN1KMT2AHDAC6 | |
| SCHEMBL12636656 | 0.87 | HTT (0.41) | HTTACSS2MEN1KMT2AHDAC6 | |
| SCHEMBL2020396 | 0.85 | HTT (0.48) | HTTACSS2MEN1KMT2AHDAC6 | |
| SCHEMBL12635756 | 0.85 | HTT (0.49) | HTTACSS2MEN1KMT2AHDAC6 | |
| SCHEMBL2020165 | 0.84 | ACSS2 (0.46) | HTTACSS2MEN1KMT2AHDAC6 | |
| SCHEMBL2040435 | 0.83 | HTT (0.45) | HTTACSS2MEN1KMT2ATP53 | |
| SCHEMBL2021620 | 0.83 | HTT (0.45) | HTTACSS2MEN1KMT2A | |
| SCHEMBL2014823 | 0.82 | HTT (0.45) | HTTMEN1KMT2ATP53LMNA | |
| SCHEMBL2016331 | 0.82 | HTT (0.52) | HTTACSS2MEN1KMT2ATP53 | |
| SCHEMBL2015541 | 0.81 | HTT (0.46) | HTTACSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011079087-A1 | ENAC BLOCKERS | GLAXO GROUP LIMITED (GB) | 2011-06-30 | — | — | WO | disclosed |