SCHEMBL20172765

SCHEMBL20172765

CN(c1cc2ccccc2c2ccccc12)c1cccc2c1oc1ccccc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.38
AHR P35869 1/20 0.36
SIGMAR1 Q99720 1/20 0.34
KMT2A Q03164 3/20 0.34
MEN1 O00255 2/20 0.34
CYP2C19 P33261 1/20 0.34
PGR P06401 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.33
KDM4E B2RXH2 4/20 0.33
ALDH1A1 P00352 3/20 0.33
LMNA P02545 2/20 0.33
MAOA P21397 2/20 0.33
GAA P10253 1/20 0.33
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
MAPT P10636 2/20 0.32
POLB P06746 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17737614 0.85 ALOX5 (0.39) ALOX5AHRKMT2AMEN1CYP2C19
SCHEMBL18841407 0.85 ALOX5 (0.39) ALOX5AHRKMT2AMEN1CYP2C19
SCHEMBL20172763 0.85 SIGMAR1 (0.45) ALOX5AHRSIGMAR1KMT2AMEN1
SCHEMBL22669825 0.81 ALOX5 (0.36) ALOX5AHRSIGMAR1KMT2AMEN1
SCHEMBL22671439 0.80 ALOX5 (0.35) ALOX5AHRKMT2AMEN1L3MBTL1
SCHEMBL20172791 0.79 PGR (0.40) ALOX5AHRKMT2AMEN1CYP2C19
SCHEMBL24826862 0.79 ALOX5 (0.37) ALOX5AHRSIGMAR1KMT2AMEN1
SCHEMBL20172764 0.79 CYP1A2 (0.38) ALOX5AHRSIGMAR1KMT2AMEN1
SCHEMBL25769013 0.79 HPRT1 (0.39) ALOX5KMT2ACYP2C19L3MBTL1KDM4E
SCHEMBL14295302 0.79 ALOX5 (0.39) ALOX5AHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10651411-B2 Compound and organic light emitting device containing same LG CHEM, LTD. (KR) 2020-05-12 US disclosed
US-20190152919-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2019-05-23 US disclosed
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME LG CHEM, LTD. (KR) 2018-05-24 US disclosed
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME LG CHEM, LTD. (KR) 2018-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME CRY1, CRY2, OR10J3 ALOX5 695/4885AHR 375/4885SIGMAR1 1467/4885
US-20190152919-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME OR10J3, ETV6, ESR1 ALOX5 2172/4885AHR 1313/4885SIGMAR1 2480/4885
US-10651411-B2 Compound and organic light emitting device containing same CRY1, CRY2, OR10J3 ALOX5 695/4885AHR 375/4885SIGMAR1 1467/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.