Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 2/20 | 0.31 |
| ▸ | RORA | P35398 | 2/20 | 0.31 |
| ▸ | RORC | P51449 | 2/20 | 0.31 |
| ▸ | RORB | Q92753 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL861236 | 0.92 | RORA (0.33) | PTGES2PGRRORARORCRORB | |
| SCHEMBL841591 | 0.86 | PGR (0.33) | PGRRORARORCRORB | |
| SCHEMBL19236218 | 0.84 | PTGES2 (0.32) | PTGES2 | |
| SCHEMBL840348 | 0.82 | PGR (0.35) | PGRRORARORCRORB | |
| SCHEMBL13286933 | 0.82 | MAPT (0.33) | — | |
| SCHEMBL20173562 | 0.80 | PTGES2 (0.34) | PTGES2PGRRORARORCRORB | |
| SCHEMBL840965 | 0.79 | LMNA (0.34) | — | |
| SCHEMBL21917530 | 0.79 | IKBKB (0.33) | — | |
| SCHEMBL23966490 | 0.79 | — | — | |
| SCHEMBL861241 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11322696-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2022-05-03 | — | — | US | disclosed |
| US-11121327-B2 | Spiro-condensed lactam compounds for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2021-09-14 | — | — | US | disclosed |
| US-10629817-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2020-04-21 | — | — | US | disclosed |
| US-20180145260-A1 | MATERIALS FOR ORGANIC ELECTRLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180145260-A1 | MATERIALS FOR ORGANIC ELECTRLUMINESCENT DEVICES | KCNB2, KCNB1, GJB2 | PTGES2 1931/4885PGR 1007/4885RORA 3502/4885 |
| US-11121327-B2 | Spiro-condensed lactam compounds for organic electroluminescent devices | PORCN, COASY, AAAS | PTGES2 2662/4885PGR 3740/4885RORA 1637/4885 |
| US-11322696-B2 | Metal complexes | AP1M1, AP3M1, AP2M1 | PTGES2 3137/4885PGR 2915/4885RORA 3211/4885 |
| US-10629817-B2 | Materials for organic electroluminescent devices | KCNB2, KCNB1, GJB2 | PTGES2 1875/4885PGR 1330/4885RORA 3858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.