SCHEMBL841591

SCHEMBL841591

Cc1cccc(C)c1-c1cnc2c3ccccc3c3cc(CC(C)(C)C)ccc3n12

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PGR P06401 3/20 0.33
RORA P35398 3/20 0.33
RORC P51449 3/20 0.33
RORB Q92753 3/20 0.33
SMO Q99835 1/20 0.31
TP53 P04637 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12759727 0.86 WEE1 (0.30)
SCHEMBL20173573 0.86 PTGES2 (0.32) PGRRORARORCRORB
SCHEMBL861800 0.85 NR1H2 (0.34) PGRRORARORCRORB
SCHEMBL861222 0.85
SCHEMBL19236218 0.85 PTGES2 (0.32)
SCHEMBL21721874 0.84
SCHEMBL23966490 0.83
SCHEMBL25752867 0.83
SCHEMBL24041878 0.82
SCHEMBL29631725 0.82 PGR (0.38) PGRRORARORCRORBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12030890-B2 Compounds with diazadibenzofurane or diazadibenzothiophene structures MERCK PATENT GMBH (DE) 2024-07-09 US disclosed
US-11641775-B2 Compounds and organic electronic devices MERCK PATENT GMBH (DE) 2023-05-02 US disclosed
US-11530224-B2 Compounds with diazadibenzofurane or diazadibenzothiophene structures MERCK PATENT GMBH (DE) 2022-12-20 US disclosed
US-11329233-B2 Heterocyclic compounds for use in electronic devices MERCK PATENT GMBH (DE) 2022-05-10 US disclosed
US-11322696-B2 Metal complexes MERCK PATENT GMBH (DE) 2022-05-03 US disclosed
US-11121323-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2021-09-14 US disclosed
US-20210151682-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2021-05-20 US disclosed
US-10971689-B2 Triphenylene-based materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2021-04-06 US disclosed
US-10957859-B2 Heterocyclic compounds for use in electronic devices MERCK PATENT GMBH (DE) 2021-03-23 US disclosed
US-10944058-B2 Compounds and organic electronic devices MERCK PATENT GMBH (DE) 2021-03-09 US disclosed
US-8142909-B2 Blue phosphorescent imidazophenanthridine materials UNIVERSAL DISPLAY CORPORATION (US) 2012-03-27 US disclosed
US-8142909-B2 Blue phosphorescent imidazophenanthridine materials UNIVERSAL DISPLAY CORPORATION (US) 2012-03-27 US disclosed
US-8142909-B2 Blue phosphorescent imidazophenanthridine materials UNIVERSAL DISPLAY CORPORATION (US) 2012-03-27 US disclosed
US-20110050093-A1 METHOD OF FORMING METAL COMPLEX COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 US disclosed
US-20110050093-A1 METHOD OF FORMING METAL COMPLEX COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 US disclosed
WO-2008156879-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2008-12-24 WO disclosed
WO-2008156879-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2008-12-24 WO disclosed
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION 2008-12-04 US disclosed
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION 2008-12-04 US disclosed
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION 2008-12-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10944058-B2 Compounds and organic electronic devices ETV6, CYP2C19, AFF2 PGR 2142/4885RORA 552/4885RORC 218/4885
US-20210151682-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES ETV6, CYP2C19, AFF2 PGR 2142/4885RORA 552/4885RORC 218/4885
US-11641775-B2 Compounds and organic electronic devices ETV6, CYP2C19, AFF2 PGR 2142/4885RORA 552/4885RORC 218/4885
US-20110050093-A1 METHOD OF FORMING METAL COMPLEX COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE ZFR, PORCN, OR10J3 PGR 3202/4885RORA 2945/4885RORC 2265/4885
US-10957859-B2 Heterocyclic compounds for use in electronic devices DDT, VDAC2, VDAC3 PGR 1405/4885RORA 1635/4885RORC 717/4885
US-11329233-B2 Heterocyclic compounds for use in electronic devices NQO1, DDT, ETV6 PGR 1265/4885RORA 1651/4885RORC 990/4885
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS IK, CRY1, MAP1LC3C PGR 3621/4885RORA 2304/4885RORC 1702/4885
US-11121323-B2 Materials for electronic devices CYP2C19, EPHX1, EPX PGR 656/4885RORA 1957/4885RORC 1557/4885
US-11322696-B2 Metal complexes AP1M1, AP3M1, AP2M1 PGR 2915/4885RORA 3211/4885RORC 2161/4885
US-12030890-B2 Compounds with diazadibenzofurane or diazadibenzothiophene structures DDT, ESD, DBF4 PGR 4085/4885RORA 4315/4885RORC 3963/4885
US-11530224-B2 Compounds with diazadibenzofurane or diazadibenzothiophene structures DDT, ESD, DBF4 PGR 4085/4885RORA 4315/4885RORC 3963/4885
US-10971689-B2 Triphenylene-based materials for organic electroluminescent devices TERT, PIEZO1, EFNA1 PGR 1297/4885RORA 3472/4885RORC 2931/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.