Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.44 |
| ▸ | HMGCR | P04035 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 7/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20176655 | 0.91 | ALOX5 (0.40) | ALOX5HMGCRGABRA1GABRB2PRKCI | |
| SCHEMBL1022126 | 0.87 | PTPN1 (0.47) | ALOX5GABRA1GABRB2PTPN1 | |
| SCHEMBL11612512 | 0.86 | CA1 (0.54) | ALOX5HMGCRGABRA1GABRB2PRKCI | |
| SCHEMBL5140860 | 0.85 | TYR (0.50) | ALOX5PTGS2 | |
| SCHEMBL1760574 | 0.84 | PTPN1 (0.53) | ALOX5HMGCRGABRA1GABRB2PRKCI | |
| SCHEMBL21790849 | 0.84 | CA1 (0.57) | ALOX5HMGCRGABRA1GABRB2GABRA5 | |
| SCHEMBL21790848 | 0.84 | CA1 (0.63) | ALOX5GABRA1GABRB2GABRA5GABRA3 | |
| SCHEMBL1022177 | 0.82 | PTPN1 (0.47) | ALOX5GABRA1GABRB2PTPN1DHFR | |
| SCHEMBL1021760 | 0.82 | AMY1A (0.47) | ALOX5HMGCRGABRA1GABRB2PRKCI | |
| SCHEMBL1023215 | 0.82 | DHFR (0.45) | ALOX5HMGCRGABRA1GABRB2PRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10329243-B2 | Biphenyl derivative and uses thereof | XI'AN LIBANG PHARMACEUTICAL CO., LTD (CN) | 2019-06-25 | — | — | US | disclosed |
| US-10329243-B2 | Biphenyl derivative and uses thereof | XI'AN LIBANG PHARMACEUTICAL CO., LTD (CN) | 2019-06-25 | — | — | US | disclosed |
| US-20180141895-A1 | DIPHENYL DERIVATIVE AND USES THEREOF | XI'AN LIBANG PHARMACEUTICAL CO., LTD (CN) | 2018-05-24 | — | — | US | disclosed |
| US-20180141895-A1 | DIPHENYL DERIVATIVE AND USES THEREOF | XI'AN LIBANG PHARMACEUTICAL CO., LTD (CN) | 2018-05-24 | — | — | US | disclosed |
| US-20180141895-A1 | DIPHENYL DERIVATIVE AND USES THEREOF | XI'AN LIBANG PHARMACEUTICAL CO., LTD (CN) | 2018-05-24 | — | — | US | disclosed |
| EP-3246304-A2 | DIPHENYL DERIVATIVE AND USES THEREOF | Xi'an Libang Pharmaceutical Co., Ltd (CN) | 2017-11-22 | — | — | EP | disclosed |
| EP-3246304-A2 | DIPHENYL DERIVATIVE AND USES THEREOF | Xi'an Libang Pharmaceutical Co., Ltd (CN) | 2017-11-22 | — | — | EP | disclosed |
| WO-2016112875-A2 | DIPHENYL DERIVATIVE AND USES THEREOF | 西安力邦制药有限公司 | 2016-07-21 | — | — | WO | disclosed |
| US-9315435-B2 | Method for producing hydroxyphenylcyclohexanol compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-04-19 | — | — | US | disclosed |
| US-20150141707-A1 | METHOD FOR PRODUCING HYDROXYPHENYLCYCLOHEXANOL COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-05-21 | — | — | US | disclosed |
| EP-2842930-A1 | METHOD FOR PRODUCING HYDROXYPHENYLCYCLOHEXANOL COMPOUND | Sumitomo Chemical Company Limited (JP) | 2015-03-04 | — | — | EP | disclosed |
| EP-0458417-B1 | Adducts of phenolic compounds and cyclic terpenes and derivatives of said adducts | SHELL INT RESEARCH (NL) | 1996-04-17 | — | — | EP | disclosed |
| US-5141974-A | Curable polyepoxide and phenolic resin copolymer; molding material for encapsulating electrical components | SHELL OIL COMPANY (US) | 1992-08-25 | — | — | US | disclosed |
| EP-0458417-A2 | Adducts of phenolic compounds and cyclic terpenes and derivatives of said adducts | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-11-27 | — | — | EP | disclosed |
| EP-0403022-A2 | Encapsulating epoxy resin composition | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-12-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150141707-A1 | METHOD FOR PRODUCING HYDROXYPHENYLCYCLOHEXANOL COMPOUND | HSD11B2, CYP21A2, CYP11B2 | ALOX5 2196/4885HMGCR 600/4885GABRA1 1252/4885 |
| US-10329243-B2 | Biphenyl derivative and uses thereof | PPARD, PCSK9, UGT2B7 | ALOX5 741/4885HMGCR 698/4885GABRA1 140/4885 |
| US-20180141895-A1 | DIPHENYL DERIVATIVE AND USES THEREOF | PPARD, DPP3, DPP7 | ALOX5 654/4885HMGCR 1193/4885GABRA1 547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.