Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.48 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.48 |
| ▸ | PSMB6 | P28072 | 2/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.48 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.48 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.48 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.48 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.48 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.48 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.48 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20250628 | 0.88 | ALDH1A1 (0.54) | HPGDCYP1A2CYP2C19GPR139ALDH1A1 | |
| SCHEMBL21581972 | 0.83 | ALDH1A1 (0.58) | HPGDCYP1A2CYP2C19GPR139ALDH1A1 | |
| SCHEMBL16252980 | 0.77 | ALDH1A1 (0.62) | HPGDCYP1A2CYP2C19GPR139ALDH1A1 | |
| SCHEMBL7218397 | 0.77 | LMNA (0.67) | HPGDCYP1A2CYP2C19GPR139ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL27375088 | 0.75 | LMNA (0.65) | HPGDCYP1A2CYP2C19GPR139ALDH1A1 | |
| SCHEMBL8002583 | 0.75 | ALDH1A1 (0.64) | HPGDCYP1A2CYP2C19GPR139ALDH1A1 | |
| SCHEMBL8001466 | 0.74 | ALDH1A1 (0.67) | HPGDCYP1A2CYP2C19GPR139ALDH1A1 | |
| SCHEMBL21203065 | 0.72 | GPR139 (0.61) | HPGDCYP1A2CYP2C19GPR139ALDH1A1 | |
| SCHEMBL20257210 | 0.72 | PSMB5 (0.63) | GPR139PSMB8PSMB9PSMB6PSMB5 | |
| SCHEMBL6357804 | 0.71 | ALDH1A1 (0.62) | HPGDCYP1A2CYP2C19GPR139ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018092723-A1 | Ras PROTEIN DEGRADATION INDUCING MOLECULE AND PHARMACEUTICAL COMPOSITION | 学校法人東京理科大学 | 2018-05-24 | — | — | WO | disclosed |
| WO-2018092725-A1 | p53 DEGRADATION INDUCING MOLECULE AND PHARMACEUTICAL COMPOSITION | 学校法人東京理科大学 | 2018-05-24 | — | — | WO | disclosed |