Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 5/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.39 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20177640 | 0.80 | DPP4 (0.38) | USP2KDM1AKDM4EKMT2AMEN1 | |
| SCHEMBL20177777 | 0.70 | FPR2 (0.44) | KMT2AMEN1MAPTHTTNPC1 | |
| SCHEMBL20177496 | 0.69 | GRM2 (0.44) | USP2KDM4EKMT2AMEN1MAPT | |
| SCHEMBL20177639 | 0.69 | GRM2 (0.44) | USP2KDM4EKMT2AMEN1MAPT | |
| SCHEMBL20177583 | 0.69 | FPR1 (0.41) | USP2KDM4EKMT2AMEN1MAPT | |
| SCHEMBL28581918 | 0.64 | USP2 (0.51) | USP2KDM4EKMT2AMEN1HTT | |
| SCHEMBL28587695 | 0.64 | USP2 (0.51) | USP2KDM4EKMT2AMEN1HTT | |
| SCHEMBL3034589 | 0.64 | HTT (0.41) | USP2KCNH2KMT2AMEN1HTT | |
| SCHEMBL20177536 | 0.60 | KDM1A (0.40) | KDM1AKCNH2MAOBRCOR1KDM1B | |
| SCHEMBL29941288 | 0.59 | ALDH1A1 (0.40) | USP2KDM4EGRM2RECQLTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018092916-A1 | NITROGEN-CONTAINING POLYCYCLIC HETEROCYCLIC DERIVATIVE | 宇部興産株式会社 | 2018-05-24 | — | — | WO | disclosed |