Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | FPR1 | P21462 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20177642 | 0.81 | SMN1; SMN2 (0.39) | HTTPKMSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL20177842 | 0.76 | FPR1 (0.53) | FPR1FPR2 | |
| SCHEMBL20177846 | 0.75 | KDM1A (0.40) | HTTPKMSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL20177565 | 0.74 | FPR1 (0.43) | HTTPKMSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL20177637 | 0.73 | FPR1 (0.44) | HTTPKMSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL20177925 | 0.70 | FPR2 (0.46) | HTTPKMSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL20177499 | 0.69 | SMN1; SMN2 (0.37) | HTTPKMSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL20177614 | 0.67 | CTSL (0.42) | ALDH1A1KMT2AFPR2MEN1GAA | |
| SCHEMBL20177511 | 0.66 | FPR2 (0.67) | FPR1FPR2 | |
| SCHEMBL20177886 | 0.66 | FPR2 (0.50) | HTTPKMSMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018092916-A1 | NITROGEN-CONTAINING POLYCYCLIC HETEROCYCLIC DERIVATIVE | 宇部興産株式会社 | 2018-05-24 | — | — | WO | disclosed |