Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20177560 | 0.86 | ALDH1A1 (0.43) | ALDH1A1MAPTMAPK1GRM5KMT2A | |
| SCHEMBL20177902 | 0.82 | GRM4 (0.39) | GRM5KMT2A | |
| SCHEMBL20177653 | 0.81 | GSK3B (0.48) | ALDH1A1MAPTGSK3BHTTKMT2A | |
| SCHEMBL20177834 | 0.68 | PDE4A (0.44) | MAPTGRM5SMN1; SMN2POLB | |
| SCHEMBL7941772 | 0.65 | KMT2A (0.49) | ALDH1A1MAPTMAPK1L3MBTL1HTT | |
| SCHEMBL29740649 | 0.65 | MAPT (0.47) | ALDH1A1MAPTPKMMAPK1L3MBTL1 | |
| SCHEMBL1628707 | 0.65 | MAPT (0.47) | ALDH1A1MAPTPKMMAPK1L3MBTL1 | |
| SCHEMBL11183526 | 0.64 | ALDH1A1 (0.50) | ALDH1A1MAPTMAPK1GSK3BL3MBTL1 | |
| SCHEMBL10620885 | 0.62 | MAPT (0.53) | ALDH1A1MAPTMAPK1GSK3BL3MBTL1 | |
| SCHEMBL1274938 | 0.61 | HTT (0.73) | ALDH1A1MAPTMAPK1L3MBTL1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018092916-A1 | NITROGEN-CONTAINING POLYCYCLIC HETEROCYCLIC DERIVATIVE | 宇部興産株式会社 | 2018-05-24 | — | — | WO | disclosed |