SCHEMBL20180689

SCHEMBL20180689

c1ccc(B2N(c3ccc(-c4ccc5c6ccccc6c6ccccc6c5c4)cc3)B(c3ccccc3)N3B(c4ccccc4)N(c4ccc(-c5ccc6c7ccccc7c7ccccc7c6c5)cc4)B(c4ccccc4)N23)cc1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 1/20 0.31
PLA2G4A P47712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20180700 0.98 PLA2G2A (0.31) PLA2G2APLA2G4A
SCHEMBL20180755 0.83 FAAH (0.33) PLA2G2APLA2G4A
SCHEMBL20735422 0.79 FAAH (0.33) PLA2G2APLA2G4A
SCHEMBL20180803 0.79
SCHEMBL20180684 0.79
SCHEMBL20180734 0.77 FAAH (0.32)
SCHEMBL20180801 0.76
SCHEMBL20180685 0.76
SCHEMBL1614546 0.72 ALDH1A1 (0.50) PLA2G2APLA2G4A
SCHEMBL14479463 0.72 ALDH1A1 (0.50) PLA2G2APLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180226580-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2018-08-09 US disclosed
US-20180145264-A1 Organic Electroluminescent Device; A Charge Transporting Material For The Organic Electroluminescent Device; And A Luminescent Device, A Display Device And A Lighting System Using The Organic Electroluminescent Device UDC IRELAND LTD (IE) 2018-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180145264-A1 Organic Electroluminescent Device; A Charge Transporting Material For The Organic Electroluminescent Device; And A Luminescent Device, A Display Device And A Lighting System Using The Organic Electroluminescent Device SLC43A1, SLC6A19, AOC3 PLA2G2A 3181/4885PLA2G4A 3825/4885
US-20180226580-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SLCO4C1, SLCO2A1, SLCO2B1 PLA2G2A 1991/4885PLA2G4A 3381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.