Sugi Predict

Sugi Predict / Compounds / SCHEMBL201819

SCHEMBL201819

SCHEMBL201819

O=C1CNCCC(C(=O)O)N1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CAD P27708 2/20 0.41
▸ TSHR P16473 2/20 0.40
▸ PMP22 Q01453 2/20 0.40
▸ GABRP O00591 1/20 0.40
▸ GABRD O14764 1/20 0.40
▸ GABRA1 P14867 1/20 0.40
▸ GABRB1 P18505 1/20 0.40
▸ GABRG2 P18507 1/20 0.40
▸ GABRB3 P28472 1/20 0.40
▸ GABRA5 P31644 1/20 0.40
▸ GABRA3 P34903 1/20 0.40
▸ GABRA2 P47869 1/20 0.40
▸ GABRB2 P47870 1/20 0.40
▸ GABRA4 P48169 1/20 0.40
▸ GABRE P78334 1/20 0.40
▸ GABRA6 Q16445 1/20 0.40
▸ GABRG1 Q8N1C3 1/20 0.40
▸ GABRG3 Q99928 1/20 0.40
▸ GABRQ Q9UN88 1/20 0.40
▸ EGLN1 Q9GZT9 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4397383 0.79 CAD (0.43) CADTSHRPMP22EGLN1CYP2D6
SCHEMBL6696989 0.79 CAD (0.43) CADTSHRPMP22EGLN1CYP2D6
SCHEMBL185894 0.79 CAD (0.43) CADTSHRPMP22EGLN1CYP2D6
Pidolic Acid SCHEMBL1239532 0.74 CAD (0.46) CADTSHRPMP22EGLN1CYP2D6
Pidolic Acid SCHEMBL15791 0.74 — —
Pidolic Acid SCHEMBL7554345 0.74 CAD (0.46) CADTSHRPMP22EGLN1CYP2D6
Pidolic Acid SCHEMBL29479230 0.74 — —
Pidolic Acid SCHEMBL10937920 0.74 CAD (0.46) CADTSHRPMP22EGLN1CYP2D6
Pidolic Acid SCHEMBL152441 0.74 CAD (0.46) CADTSHRPMP22EGLN1CYP2D6
Pidolic Acid SCHEMBL15790 0.74 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8580746-B2 Amide linkage cyclic natriuretic peptide constructs PALATIN TECHNOLOGIES, INC. (US) 2013-11-12 — — US disclosed
US-8580747-B2 Cyclic natriuretic peptide constructs PALATIN TECHNOLOGIES, INC. (US) 2013-11-12 — — US disclosed
EP-2001518-B1 CYCLIC NATRIURETIC PEPTIDE CONSTRUCTS PALATIN TECHNOLOGIES INC (US) 2013-07-10 — — EP disclosed
US-8114844-B2 Linear and cyclic melanocortin receptor-specific peptidomimetics PALATIN TECHNOLOGIES, INC. (US) 2012-02-14 — — US disclosed
EP-2004352-B1 AMINO ACID SURROGATES FOR PEPTIDIC CONSTRUCTS PALATIN TECHNOLOGIES INC (US) 2012-01-04 — — EP disclosed
US-20110263818-A1 Peptidic Constructs with Amino Acid Surrogates PALATIN TECHNOLOGIES, INC. (US) 2011-10-27 — — US disclosed
US-7964181-B2 Amino acid surrogates for peptidic constructs PALATIN TECHNOLOGIES, INC. (US) 2011-06-21 — — US disclosed
US-7795221-B2 Linear natriuretic peptide constructs PALATIN TECHNOLOGIES, INC. (US) 2010-09-14 — — US disclosed
US-20100075895-A1 Cyclic Natriuretic Peptide Constructs PALATIN TECHNOLOGIES, INC. (US) 2010-03-25 — — US disclosed
US-20100035821-A1 Amide Linkage Cyclic Natriuretic Peptide Constructs PALATIN TECHNOLOGIES, INC. (US) 2010-02-11 — — US disclosed
EP-2004633-A2 LINEAR NATRIURETIC PEPTIDE CONSTRUCTS Palatin Technologies, Inc. (US) 2008-12-24 — — EP disclosed
EP-2004352-A2 AMINO ACID SURROGATES FOR PEPTIDIC CONSTRUCTS Palatin Technologies, Inc. (US) 2008-12-24 — — EP disclosed
EP-2001518-A2 CYCLIC NATRIURETIC PEPTIDE CONSTRUCTS Palatin Technologies, Inc. (US) 2008-12-17 — — EP disclosed
WO-2007115164-A9 AMINO ACID SURROGATES FOR PEPTIDIC CONSTRUCTS PALATIN TECHNOLOGIES INC (US) 2007-11-29 — — WO disclosed
US-20070265206-A1 Cyclic Natriuretic Peptide Constructs PALATIN TECHNOLOGIES, INC. (US) 2007-11-15 — — US disclosed
US-20070260040-A1 Amino Acid Surrogates for Peptidic Constructs PALATIN TECHNOLOGIES, INC. (US) 2007-11-08 — — US disclosed
WO-2007115182-A2 LINEAR NATRIURETIC PEPTIDE CONSTRUCTS PALATIN TECHNOLOGIES, INC. (US) 2007-10-11 — — WO disclosed
WO-2007115164-A2 AMINO ACID SURROGATES FOR PEPTIDIC CONSTRUCTS PALATIN TECHNOLOGIES, INC. (US) 2007-10-11 — — WO disclosed
WO-2007115175-A2 CYCLIC NATRIURETIC PEPTIDE CONSTRUCTS PALATIN TECHNOLOGIES, INC. (US) 2007-10-11 — — WO disclosed
US-20070232546-A1 Linear Natriuretic Peptide Constructs PALATIN TECHNOLOGIES, INC. (US) 2007-10-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110263818-A1 Peptidic Constructs with Amino Acid Surrogates ARGLU1, QRFPR, ARG1 CAD 3346/4885TSHR 111/4885PMP22 1385/4885
US-20070265206-A1 Cyclic Natriuretic Peptide Constructs NPR1, NPR3, NPPA CAD 293/4885TSHR 44/4885PMP22 1836/4885
US-20070260040-A1 Amino Acid Surrogates for Peptidic Constructs ARGLU1, ARG1, QRFPR CAD 3526/4885TSHR 250/4885PMP22 1968/4885
US-20100035821-A1 Amide Linkage Cyclic Natriuretic Peptide Constructs NPR1, NPR3, NPPA CAD 459/4885TSHR 63/4885PMP22 2814/4885
US-20070232546-A1 Linear Natriuretic Peptide Constructs NPR1, NPR3, NPPA CAD 345/4885TSHR 40/4885PMP22 2038/4885
US-20100075895-A1 Cyclic Natriuretic Peptide Constructs NPR1, NPR3, NPPA CAD 293/4885TSHR 44/4885PMP22 1836/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.