Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20162922 | 0.85 | HSP90AA1 (0.31) | HSP90AA1 | |
| SCHEMBL20182182 | 0.82 | DYRK1A (0.32) | — | |
| SCHEMBL20181888 | 0.79 | ADK (0.44) | MEN1KMT2A | |
| SCHEMBL20351604 | 0.72 | PDK2 (0.30) | — | |
| SCHEMBL20182247 | 0.67 | ADK (0.44) | — | |
| SCHEMBL6773652 | 0.65 | CRHR1 (0.53) | — | |
| SCHEMBL14277045 | 0.63 | CRHR1 (0.43) | — | |
| SCHEMBL1636385 | 0.63 | CRHR1 (0.43) | — | |
| SCHEMBL27613787 | 0.63 | FPR3 (0.33) | — | |
| SCHEMBL6214728 | 0.62 | FPR3 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018094137-A1 | PYRROLOPYRIMIDINES AS CFTR POTENTIATORS | CYSTIC FIBROSIS FOUNDATION THERAPEUTICS INC. (US) | 2018-05-24 | — | — | WO | disclosed |