SCHEMBL20182728

SCHEMBL20182728

COC(=O)OCc1ccc2ccccc2c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 1/20 0.55
SLC1A3 P43003 1/20 0.51
SLC1A2 P43004 1/20 0.51
SLC1A1 P43005 1/20 0.51
PPARG P37231 3/20 0.51
PPARD Q03181 2/20 0.51
PPARA Q07869 2/20 0.51
CTSL P07711 1/20 0.48
CTSB P07858 1/20 0.48
CTSS P25774 1/20 0.48
POLB P06746 1/20 0.48
NCOA2 Q15596 1/20 0.48
NCOA1 Q15788 1/20 0.48
CTDSP1 Q9GZU7 1/20 0.48
NCOA3 Q9Y6Q9 1/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
CYP1A2 P05177 1/20 0.47
CYP2A6 P11509 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29404861 0.85 TACR1 (0.48) TACR1SLC1A3SLC1A2SLC1A1PPARG
SCHEMBL6519797 0.84 SLC1A3 (0.48) TACR1SLC1A3SLC1A2SLC1A1CYP1A2
SCHEMBL14011321 0.83 TACR1 (0.52) TACR1SLC1A3SLC1A2SLC1A1PPARG
SCHEMBL6910495 0.83 SLC1A3 (0.50) TACR1SLC1A3SLC1A2SLC1A1CYP1A2
SCHEMBL487508 0.83 ALDH1A1 (0.61) TACR1SLC1A3SLC1A2SLC1A1CYP1A2
SCHEMBL28936084 0.82 CYP1A2 (0.54) TACR1SLC1A3SLC1A2SLC1A1CYP1A2
SCHEMBL12057416 0.82 TOP2A (0.54) TACR1SLC1A3SLC1A2SLC1A1CTSL
SCHEMBL6443296 0.81 SLC1A3 (0.51) TACR1SLC1A3SLC1A2SLC1A1CYP1A2
SCHEMBL6443298 0.81 SLC1A3 (0.55) TACR1SLC1A3SLC1A2SLC1A1PPARG
SCHEMBL23645097 0.81 SLC1A3 (0.56) TACR1SLC1A3SLC1A2SLC1A1CTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018091370-A1 ELECTROCHEMICAL METHOD FOR PRODUCING ARYL ALKYL CARBONATES AND DIARYL CARBONATES COVESTRO DEUTSCHLAND AG (DE) 2018-05-24 WO disclosed