SCHEMBL2018342

SCHEMBL2018342

CCN(N)c1ccc2c(c1)C(=O)c1ccccc1C2=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 7/20 0.53
NPC1 O15118 6/20 0.53
ALDH1A1 P00352 6/20 0.53
SMN1; SMN2 Q16637 5/20 0.53
MAPK1 P28482 4/20 0.53
LMNA P02545 3/20 0.53
L3MBTL1 Q9Y468 3/20 0.53
MAPT P10636 2/20 0.53
CYP3A4 P08684 3/20 0.48
TSHR P16473 2/20 0.48
ELANE P08246 1/20 0.48
TP53 P04637 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
CYP1A2 P05177 3/20 0.48
CASP3 P42574 2/20 0.47
SENP8 Q96LD8 2/20 0.47
SENP7 Q9BQF6 2/20 0.47
SENP6 Q9GZR1 2/20 0.47
ATM Q13315 1/20 0.47
CYP2D6 P10635 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6850488 0.84 ALDH1A1 (0.57) RAB9ANPC1ALDH1A1SMN1; SMN2MAPK1
SCHEMBL6444104 0.82 MAPK1 (0.59) RAB9ANPC1ALDH1A1SMN1; SMN2MAPK1
SCHEMBL6688342 0.81 RAB9A (0.51) RAB9ANPC1ALDH1A1SMN1; SMN2MAPK1
SCHEMBL18984698 0.77 MAPK1 (0.54) RAB9ANPC1ALDH1A1SMN1; SMN2MAPK1
SCHEMBL6131235 0.77 NR3C2 (0.51) RAB9ANPC1ALDH1A1SMN1; SMN2MAPK1
SCHEMBL14982137 0.77 ALDH1A1 (0.62) RAB9ANPC1ALDH1A1SMN1; SMN2MAPK1
SCHEMBL3091326 0.77 ALDH1A1 (0.61) RAB9ANPC1ALDH1A1SMN1; SMN2MAPK1
SCHEMBL18984663 0.77 ELANE (0.55) RAB9ANPC1ALDH1A1SMN1; SMN2MAPK1
Phosphoric Acid SCHEMBL6340607 0.76 CYP1A2 (0.50) RAB9ANPC1ALDH1A1SMN1; SMN2MAPK1
SCHEMBL4650028 0.76 ALDH1A1 (0.48) RAB9ANPC1ALDH1A1SMN1; SMN2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023118332-A1 COMPOSITION COMPRISING TWO POLYOLS DIFFERENT FROM ONE ANOTHER, AN ALKALINE AGENT AND A DYE L'OREAL (FR) 2023-06-29 WO disclosed
US-10005259-B2 Packaging device for a hair dyeing product L'OREAL (FR) 2018-06-26 US disclosed
US-9125815-B2 Agent for dyeing and/or bleaching keratinous fibres in two or more parts, comprising an alkaline composition in an inverse emulsion L'OREAL (FR) 2015-09-08 US disclosed
US-20130189206-A1 AGENT FOR DYEING AND/OR BLEACHING KERATINOUS FIBRES IN TWO OR MORE PARTS, COMPRISING AN ALKALINE COMPOSITION IN AN INVERSE EMULSION L'OREAL (FR) 2013-07-25 US disclosed
WO-2011076790-A2 METHOD FOR DYEING OR LIGHTENING KERATINOUS FIBRES IN THE PRESENCE OF VOLATILE LINEAR ALKANE(S) AND DEVICE. L'OREAL (FR) 2011-06-30 WO disclosed
CN-100548826-C Be used for packing device of cosmetic composition and uses thereof OREAL (FR) 2009-10-14 CN disclosed
US-7077873-B2 Composition for the dyeing of human keratinous fibres comprising a monocationic monoazo dye L'Oréal, SA (FR) 2006-07-18 US disclosed
US-20060154009-A1 Packaging device for a hair dyeing product L'OREAL S.A. (FR) 2006-07-13 US disclosed
CN-1799947-A Packaging device for a hair dyeing product OREAL (FR) 2006-07-12 CN disclosed
US-7018428-B2 Process for the preparation of a dyeing composition for the dyeing of keratinous fibers from pressurized steam L'OREAL (FR) 2006-03-28 US disclosed
US-20040255400-A1 Process for the preparation of a dyeing composition for the dyeing of keratinous fibers from pressurized steam L'OREAL S.A. (FR) 2004-12-23 US disclosed
US-20040127692-A1 Composition for the dyeing of human keratinous fibres comprising a monocationic monoazo dye L'OREAL S.A. (FR) 2004-07-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040127692-A1 Composition for the dyeing of human keratinous fibres comprising a monocationic monoazo dye KRT18, WNT3, DSG1 RAB9A 4801/4885NPC1 3933/4885ALDH1A1 2440/4885
US-20040255400-A1 Process for the preparation of a dyeing composition for the dyeing of keratinous fibers from pressurized steam KRT18, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, PKM RAB9A 2257/4885NPC1 4750/4885ALDH1A1 2714/4885
US-20130189206-A1 AGENT FOR DYEING AND/OR BLEACHING KERATINOUS FIBRES IN TWO OR MORE PARTS, COMPRISING AN ALKALINE COMPOSITION IN AN INVERSE EMULSION KRT18, LIPA, HBB RAB9A 1137/4885NPC1 2390/4885ALDH1A1 1082/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.