Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | FDFT1 | P37268 | 3/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 2/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3465495 | 0.87 | HTR3A (0.57) | HDAC2HDAC1HTR3AMIF | |
| SCHEMBL1523403 | 0.81 | MIF (0.57) | HDAC2HDAC1HTR3AMIF | |
| SCHEMBL30869989 | 0.80 | HDAC2 (0.60) | FFAR1FDFT1HDAC2HDAC1ABCC4 | |
| SCHEMBL10456657 | 0.79 | MIF (0.55) | HDAC2HDAC1HTR3AMIF | |
| Hydrochloric Acid SCHEMBL28503124 | 0.79 | MIF (0.55) | HDAC2HDAC1HTR3AMIF | |
| SCHEMBL29152182 | 0.79 | NAAA (0.58) | HDAC2HDAC1HTR3AMIF | |
| SCHEMBL5035695 | 0.79 | MIF (0.55) | HDAC2HDAC1HTR3AMIF | |
| SCHEMBL21694457 | 0.79 | MIF (0.55) | HDAC2HDAC1HTR3AMIF | |
| SCHEMBL9826765 | 0.78 | HTR2A (0.62) | FFAR1FDFT1HDAC2HDAC1MMP12 | |
| SCHEMBL5540653 | 0.77 | FFAR1 (0.55) | FFAR1FDFT1HDAC2HDAC1MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2890672-B1 | PROCESSES FOR PREPARING INTERMEDIATES FOR THE MANUFACTURE OF NEP INHIBITORS | NOVARTIS AG (CH) | 2018-05-30 | — | — | EP | disclosed |