Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 5/20 | 0.36 |
| ▸ | CD38 | P28907 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 2/20 | 0.34 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.34 |
| ▸ | RBP4 | P02753 | 2/20 | 0.34 |
| ▸ | PTGES | O14684 | 2/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195479 | 0.83 | KMT2A (0.38) | CD38CYP3A4 | |
| SCHEMBL20195491 | 0.79 | SSTR4 (0.40) | P2RX7KCNH2CNR2SSTR4 | |
| SCHEMBL20195623 | 0.74 | MCL1 (0.42) | CD38CYP3A4SORT1TTRDHODH | |
| SCHEMBL20195659 | 0.71 | CLCN2 (0.40) | CD38HPGDSORT1 | |
| SCHEMBL18504372 | 0.71 | STIM1 (0.34) | P2RX7CTSSRBP4CTSK | |
| SCHEMBL20195619 | 0.71 | KMT2A (0.41) | HPGD | |
| SCHEMBL22564334 | 0.70 | STIM1 (0.33) | P2RX7CTSSRBP4CTSK | |
| SCHEMBL20195628 | 0.70 | TP53 (0.44) | HPGD | |
| SCHEMBL20195656 | 0.69 | L3MBTL1 (0.50) | P2RX7CNR2 | |
| SCHEMBL17788258 | 0.69 | MRGPRX4 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |