Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.44 |
| ▸ | NPC1 | O15118 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | ATP4A | P20648 | 1/20 | 0.39 |
| ▸ | ATP4B | P51164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195529 | 0.88 | HTT (0.46) | RAB9ANPC1KMT2ATP53MEN1 | |
| SCHEMBL20195626 | 0.84 | GABRA5 (0.42) | RAB9ANPC1KMT2AMEN1CTSD | |
| SCHEMBL20195614 | 0.83 | GRM5 (0.40) | RAB9ANPC1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL20195587 | 0.82 | P2RX7 (0.43) | RAB9ANPC1KMT2ATP53MEN1 | |
| SCHEMBL20845023 | 0.79 | NPC1 (0.38) | RAB9ANPC1KMT2ATP53MEN1 | |
| SCHEMBL18504485 | 0.79 | CTSD (0.36) | RAB9ANPC1SMN1; SMN2CTSDATP4A | |
| SCHEMBL22564338 | 0.78 | CTSD (0.35) | RAB9ANPC1SMN1; SMN2CTSDATP4A | |
| SCHEMBL20195609 | 0.77 | MEN1 (0.51) | KMT2AMEN1MAPK1ALDH1A1HSD17B10 | |
| SCHEMBL20195648 | 0.77 | ALDH1A1 (0.44) | RAB9ANPC1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL20195642 | 0.74 | ALDH1A1 (0.51) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |