Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | BCR | P11274 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20197355 | 0.88 | MEN1 (0.53) | MEN1MAPTKMT2ANPC1RAB9A | |
| SCHEMBL20197228 | 0.86 | CYP1A1 (0.42) | MEN1MAPTKMT2ANPC1RAB9A | |
| SCHEMBL20197243 | 0.84 | NUDT1 (0.45) | ABL1BCRCYP19A1RHEBKDR | |
| SCHEMBL16535972 | 0.83 | PIP4K2A (0.39) | MEN1MAPTKMT2ANPC1RAB9A | |
| SCHEMBL20197303 | 0.81 | CYP1A2 (0.32) | NPC1RAB9ASMN1; SMN2KDM4ECYP1A1 | |
| SCHEMBL20197302 | 0.80 | SMN1; SMN2 (0.46) | MEN1MAPTKMT2ANPC1RAB9A | |
| SCHEMBL20197318 | 0.76 | EIF4E (0.46) | NPC1RAB9ASMN1; SMN2KDM4ECYP1A1 | |
| SCHEMBL20197336 | 0.74 | CYP19A1 (0.46) | MEN1MAPTKMT2ANPC1RAB9A | |
| SCHEMBL20197309 | 0.74 | CYP1B1 (0.41) | MEN1MAPTKMT2ANPC1RAB9A | |
| SCHEMBL20197472 | 0.73 | CYP1B1 (0.36) | MEN1MAPTKMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3038622-B1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECH LLC (US) | 2018-05-30 | — | — | EP | disclosed |