Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 2/20 | 0.39 |
| ▸ | JAK1 | P23458 | 2/20 | 0.39 |
| ▸ | TYK2 | P29597 | 2/20 | 0.39 |
| ▸ | JAK3 | P52333 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | PHGDH | O43175 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22365063 | 0.89 | FAAH (0.44) | ALDH1A1KMT2AGAAMAPK1JAK2 | |
| SCHEMBL20198110 | 0.86 | CHKA (0.42) | JAK2JAK1TYK2JAK3NPC1 | |
| SCHEMBL15263968 | 0.83 | ALDH1A1 (0.47) | ALDH1A1KMT2AGAAMAPK1JAK2 | |
| SCHEMBL15093704 | 0.83 | LMNA (0.43) | JAK2JAK1TYK2JAK3TGFBR1 | |
| SCHEMBL15266376 | 0.82 | TGFBR1 (0.39) | ALDH1A1JAK2JAK1TYK2JAK3 | |
| SCHEMBL15093900 | 0.79 | ALDH1A1 (0.48) | ALDH1A1JAK2JAK1TYK2JAK3 | |
| SCHEMBL15263832 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KMT2AGAAJAK2JAK1 | |
| SCHEMBL15100956 | 0.76 | MGLL (0.57) | — | |
| SCHEMBL18623644 | 0.75 | MGLL (0.47) | ALDH1A1KDM4EPOLB | |
| SCHEMBL21868503 | 0.75 | ALDH1A1 (0.41) | ALDH1A1KMT2AGAAMAPK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3698782-A1 | CARBAMATE COMPOUNDS FOR USE IN THERAPY | Lundbeck La Jolla Research Center, Inc. (US) | 2020-08-26 | — | — | EP | disclosed |
| EP-3326627-A1 | CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME | Abide Therapeutics, Inc. (US) | 2018-05-30 | — | — | EP | disclosed |