Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16744476 | 0.89 | KMT2A (0.53) | KMT2APKMSMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL18634071 | 0.80 | KMT2A (0.52) | KMT2APKMSMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL15100843 | 0.76 | KMT2A (0.55) | KMT2APKMSMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL20408697 | 0.75 | KMT2A (0.57) | KMT2APKMSMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL22365059 | 0.70 | MAOA (0.44) | PKMSMN1; SMN2POLBGAA | |
| SCHEMBL18634273 | 0.70 | MGLL (0.53) | KMT2APKMSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL18634072 | 0.70 | GPR183 (0.50) | KMT2APKMSMN1; SMN2POLBGAA | |
| SCHEMBL18634193 | 0.70 | F13A1 (0.46) | KMT2APKMSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL20198164 | 0.68 | HTR1A (0.45) | KMT2APKMSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL20411236 | 0.68 | PKM (0.47) | PKMSMN1; SMN2POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3326627-A1 | CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME | Abide Therapeutics, Inc. (US) | 2018-05-30 | — | — | EP | disclosed |