Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15100843 | 0.89 | KMT2A (0.55) | KMT2ANPC1RAB9AMDM2GAA | |
| SCHEMBL20408695 | 0.89 | GAA (0.56) | KMT2AGAAPKMSMN1; SMN2LMNA | |
| SCHEMBL20408696 | 0.88 | GPR183 (0.52) | KMT2AGAAMEN1PKMSMN1; SMN2 | |
| SCHEMBL18634071 | 0.86 | KMT2A (0.52) | KMT2ANPC1RAB9AMDM2GAA | |
| SCHEMBL20408703 | 0.83 | PKM (0.65) | KMT2ARAB9AGAAMEN1PKM | |
| SCHEMBL16744476 | 0.81 | KMT2A (0.53) | KMT2ANPC1RAB9AMDM2GAA | |
| SCHEMBL20408699 | 0.81 | LMNA (0.46) | KMT2AGAAMEN1PKMSMN1; SMN2 | |
| SCHEMBL20408701 | 0.81 | SMN1; SMN2 (0.62) | GAAPKMSMN1; SMN2LMNAHTT | |
| SCHEMBL20408689 | 0.80 | SLC6A9 (0.53) | KMT2AGAAMEN1SMN1; SMN2LMNA | |
| SCHEMBL18410584 | 0.78 | TGM2 (0.65) | KMT2ANPC1RAB9AMDM2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180208568-A1 | CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME | H. LUNDBECK A/S (DK) | 2018-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180208568-A1 | CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ABHD6, ABHD16A, NCEH1 | KMT2A 397/4885NPC1 1352/4885RAB9A 742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.