SCHEMBL20198221

SCHEMBL20198221

Cc1cccc(C[S+]([O-])Cc2ccccc2)c1

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.46
IDO1 P14902 2/20 0.44
TAS2R14 Q9NYV8 1/20 0.41
ACHE P22303 2/20 0.41
BACE1 P56817 2/20 0.40
CTBP2 P56545 1/20 0.40
HRH3 Q9Y5N1 1/20 0.39
BCHE P06276 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
TP53 P04637 1/20 0.38
MAPT P10636 1/20 0.38
MAOB P27338 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3570833 0.94 TAAR1 (0.50) TAAR1IDO1ACHECTBP2HRH3
SCHEMBL20198224 0.82 LMNA (0.47) TAS2R14ACHEBCHE
Ethane SCHEMBL7199050 0.81 TP53 (0.43) TAAR1IDO1ACHETP53MAPT
SCHEMBL340372 0.81 CALM1 (0.45) TAAR1IDO1TP53MAOB
Benzene SCHEMBL11030926 0.81 CALM1 (0.45) TAAR1IDO1TP53MAOB
SCHEMBL6589934 0.80 TAAR1 (0.48) TAAR1IDO1ACHECTBP2HRH3
SCHEMBL22316467 0.77 LOXL2 (0.33) MAOB
SCHEMBL22316464 0.77 IDO1 (0.33) IDO1MAOB
SCHEMBL11023124 0.75 TP53 (0.44) TAAR1IDO1ACHETP53MAPT
SCHEMBL10269439 0.75 ACHE (0.36) ACHENPSR1TP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1675930-B1 NEW MATERIALS FOR ELECTROLUMINESCENCE AND THE UTILIZATION THEREOF MERCK PATENT GMBH (DE) 2018-05-30 EP disclosed