Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28178665 | 0.82 | CYP1A2 (0.51) | ALDH1A1SMN1; SMN2HSD17B10MEN1KMT2A | |
| SCHEMBL2094826 | 0.79 | ALDH1A1 (0.43) | ALDH1A1MAPTRAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL30168174 | 0.78 | CYP11B1 (0.57) | ALDH1A1MAPTRAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL20201237 | 0.78 | ALDH1A1 (0.42) | ALDH1A1MAPTRAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL28034614 | 0.76 | MAPT (0.51) | ALDH1A1MAPTSMN1; SMN2HSD17B10MEN1 | |
| SCHEMBL9042497 | 0.76 | P2RX7 (0.42) | ALDH1A1MAPTSMN1; SMN2HSD17B10ALOX15 | |
| SCHEMBL8195797 | 0.75 | NOTUM (0.53) | ALDH1A1MAPTRAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL9042829 | 0.75 | PKM (0.45) | ALDH1A1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL2006792 | 0.74 | ALDH1A1 (0.52) | ALDH1A1MAPTSMN1; SMN2HSD17B10CYP3A4 | |
| SCHEMBL10399962 | 0.73 | BIRC5 (0.55) | ALDH1A1MAPTRAB9ASMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230167067-A1 | PHOTOREDOX-CATALYZED DIRECT C-H FUNCTIONALIZATION OF ARENES | UNIV NORTH CAROLINA CHAPEL HILL (US) | 2023-06-01 | — | — | US | disclosed |
| CN-113200983-A | Compound with pyrrolopyridine structure, preparation method and medical application | 中国药科大学 | 2021-08-03 | — | — | CN | disclosed |
| US-20180148414-A1 | PHOTOREDOX-CATALYZED DIRECT C-H FUNCTIONALIZATION OF ARENES | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180148414-A1 | PHOTOREDOX-CATALYZED DIRECT C-H FUNCTIONALIZATION OF ARENES | PPOX, AOC2, AOC3 | ALDH1A1 495/4885MAPT 3005/4885RAB9A 2766/4885 |
| US-20230167067-A1 | PHOTOREDOX-CATALYZED DIRECT C-H FUNCTIONALIZATION OF ARENES | PPOX, AOC2, AOC3 | ALDH1A1 495/4885MAPT 3005/4885RAB9A 2766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.